We know that, drugs adhere to albumin [in the blood] and fat tissue. Therefore, dug doses have been calculated to fit these anomalies. It can lead to an overdose is a second drug enters the body and displaces the first drug, therefore increasing the concentration of it,1st drug, in the body.
Here is a thought:
Why don't we place the drug in a viral capsule or a viral-like capsule, that has specific proteins expressed on the surface. The proteins should be specific enough that they activate a receptor mediated endocytosis process. This would increase the specificity of drugs. However, I am not sure whether it will avoid the problem of drugs forming non-specific binding to albumin and fat.
will answer that in the coming posts!
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