Monday, 27 October 2014

Autism

I recently found out that autistic people had a problem with identifying faces. This lies in the fact that, it is difficult for them to integrate the different structures of the face i.e. nose, eyes etc.
This is an interesting phenomenon where I think that it lies in the neuronal tracts in the visual system.

According to Jianling Chen et al., Autism is linked to genetic mutation of synapse-forming proteins, such as neurexin etc. Mutations with these proteins creates a problem in the cell-to-cell communication of neuronal cells. This might explain the inability to recognise face.

Limitation: There is no way of reversing genetic mutations, and there might be other mutated genes also involved in Autism.

Is there a way of recovering or reverse the effect of genetic mutations? If so, when is the right time to do so? and there are ethical implications regarding this?

How are the medications taking into account the genetic mutation, if there is any medication?

Investigations in this aspect might involve trying to reverse genetic mutations induced by ENU mutagenesis.

Reference
Chen et al. 2014. Synaptic proteins and receptors defects in autism spectrum disorders. Front Cell Neuroscience, 11;8:276. 

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