Rheumatoid arthritis

Rheumatoid arthritis is an auto-immune disease, where the body views and attacks the cartilage as a pathogen. It is really harmful and there are no distinct causes, however, there are genetic correlations. There is no solution to treating this disease. The patient will be given drugs that reduce the increase of immune cells in joints.

A possible solution could be to cover the MHC (a protein identifies a cell of an individual) with other accepted MHC. this would reduce the target of the immune cells and at the same time drugs should be given to reduce the effect.

Autism

I recently found out that autistic people had a problem with identifying faces. This lies in the fact that, it is difficult for them to integrate the different structures of the face i.e. nose, eyes etc.
This is an interesting phenomenon where I think that it lies in the neuronal tracts in the visual system.

According to Jianling Chen et al., Autism is linked to genetic mutation of synapse-forming proteins, such as neurexin etc. Mutations with these proteins creates a problem in the cell-to-cell communication of neuronal cells. This might explain the inability to recognise face.

Limitation: There is no way of reversing genetic mutations, and there might be other mutated genes also involved in Autism.

Is there a way of recovering or reverse the effect of genetic mutations? If so, when is the right time to do so? and there are ethical implications regarding this?

How are the medications taking into account the genetic mutation, if there is any medication?

Investigations in this aspect might involve trying to reverse genetic mutations induced by ENU mutagenesis.

Reference: 
Chen et al. 2014. Synaptic proteins and receptors defects in autism spectrum disorders. Front Cell Neuroscience, 11;8:276.