Showing posts with label auto-immune. Show all posts
Showing posts with label auto-immune. Show all posts

Wednesday, 25 November 2015

Get rid of background noise!

Sir Tim Hunt explained the complexity that arises in biological organisms in the most eloquent ways. His statement was based on the evolution of species. The previous basic pathways used to perform the task is 'replaced' efficient pathways of performing specific tasks. The basic task is actually not replaced, it is just not used, it fades into the background. But, nevertheless, it is always there. This is what make the cell a complex structure. 

As a researcher you need to know how to focus on the pathways that matter and not to be deterred by the background pathways. Going along this logic, I believe this same mindset should be used when determining the auto-immune diseases. (I have not yet checked the literature to assume that this mindset has not been used). 

The immune system is already a complex one, if we are able to extract the essential proteins involved in the disease then I believe it would lead to a quicker understanding of what goes wrong in autoimmune diseases such as myasthenia gravis. 

Image obtained from http://www.outofthewoodsnutrition.com/blog/2015/7/15/10-things-you-need-to-know-about-autoimmune-disease

Friday, 14 November 2014

Rheumatoid arthritis

Rheumatoid arthritis is an auto-immune disease, where the body views and attacks the cartilage as a pathogen. It is really harmful and there are no distinct causes, however, there are genetic correlations. There is no solution to treating this disease. The patient will be given drugs that reduce the increase of immune cells in joints.

A possible solution could be to cover the MHC (a protein identifies a cell of an individual) with other accepted MHC. this would reduce the target of the immune cells and at the same time drugs should be given to reduce the effect.