Rheumatoid arthritis is an auto-immune disease, where the body views and attacks the cartilage as a pathogen. It is really harmful and there are no distinct causes, however, there are genetic correlations. There is no solution to treating this disease. The patient will be given drugs that reduce the increase of immune cells in joints.
A possible solution could be to cover the MHC (a protein identifies a cell of an individual) with other accepted MHC. this would reduce the target of the immune cells and at the same time drugs should be given to reduce the effect.
Showing posts with label proteins. Show all posts
Showing posts with label proteins. Show all posts
Friday, 14 November 2014
Tuesday, 11 November 2014
identifying the citizens of a cell
Is there a way of identifying all the proteins active in a cell and how they interact with one another?
What is the perfect method of understanding intracellular protein-to-protein interaction? The best method so far lies in knock-outs/in experimentation, where mutation is induced. However, this method takes a longer time and even though the exact mechanism of interactions unknown.
What we need is a way of taking one cell and identifying the proteins involved, then tagging the proteins and observing how they interact with one another. The important question is HOW can this be done??
What is the perfect method of understanding intracellular protein-to-protein interaction? The best method so far lies in knock-outs/in experimentation, where mutation is induced. However, this method takes a longer time and even though the exact mechanism of interactions unknown.
What we need is a way of taking one cell and identifying the proteins involved, then tagging the proteins and observing how they interact with one another. The important question is HOW can this be done??
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